BioMarin也迅速跟进迭代研发,其升级版在研产品BMN333同样旨在实现周剂注射。早期临床结果显示BMN333的AUC水平高于其他长效CNP研究的3倍以上,公司研发主管Greg Friberg表示该药对标的正是TransCon-CNP。
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There are about 33 distinct test constants, covering every protection scenario on the 386. Each activates a different subset of the 148 product terms, encoding the specific privilege rules for that scenario. To give a feel for what the PLA does concretely, here are the possible outcomes for two tests: